Search results “Bacteroides thetaiotaomicron and humans”
Bacteroides: Fecal Indicators
Bacteroides is a genus of Gram-negative, bacillus bacteria. Bacteroides are non-endospore forming, anaerobes that comprise a significant portion of the normal human flora, particularly in the intestinal tract. Here they play an essential part in processing complex molecules into simpler ones in the host's intestines. Bacteroides are significant as an alternative fecal indicator organism since they make up such a large amount of the normal fecal bacterial flora, have a high degree of host specificity and typically have a low potential to grow in the general environment. Due to their sheer numbers, the chance of finding Bacteroides over other traditional fecal indicators, such as E. coli, are greatly increased.
Views: 4433 Paul Cochrane
Thiamine Acquisition Strategies of B. thetaiotaomicron - mSystems®
Thiamine Acquisition Strategies Impact Metabolism and Competition in the Gut Microbe Bacteroides thetaiotaomicron Variation in the ability of gut microbes to transport, synthesize, and compete for vitamin B1 (thiamine) is expected to impact the structure and stability of the microbiota, and ultimately this variation may have both direct and indirect effects on human health. Our study identifies the diverse strategies employed by gut Bacteroidetes to acquire thiamine. We demonstrate how the presence or absence of thiamine biosynthesis or transport dramatically affects the abundance of B. thetaiotaomicron in a competitive environment. This study adds further evidence that altering the presence or concentrations of watersoluble vitamins such as thiamine may be an effective method for manipulating gut community composition. In turn, targeted thiamine delivery could be used therapeutically to alter dysbiotic communities linked to disease. Doi: https://doi.org/10.1128/mSystems.00116-17 Authors: Zachary A. Costliow, Patrick H. Degnan Editor: Jack A. Gilbert, University of Chicago Published in mSystems® on 26 September 2017 mSystems® publishes preeminent work that stems from applying technologies for high-throughput analyses to achieve insights into the metabolic and regulatory systems at the scale of both the single cell and microbial communities. The scope of mSystems® encompasses all important biological and biochemical findings drawn from analyses of large data sets, as well as new computational approaches for deriving these insights. mSystems® welcomes submissions from researchers who focus on the microbiome, genomics, metagenomics, transcriptomics, metabolomics, proteomics, glycomics, bioinformatics, and computational microbiology. mSystems® provides streamlined decisions, while carrying on ASM's tradition of rigorous peer review. Subscribe to ASM's YouTube channel at https://goo.gl/mOVHlK Learn more about the American Society for Microbiology at http://www.asm.org Become a member today at http://www.asmscience.org/join Interact with us on social at: Facebook Show your support and get updates on the latest microbial offerings and news from the ASM. http://www.facebook.com/asmfan ASM International Facebook Groups Join an ASM International Facebook Group and connect with microbiologists in your region. http://www.asm.org/index.php/programs/asm-international-facebook-groups Twitter Follow all the latest news from the Society. http://www.twitter.com/ASMicrobiology Instagram Outstanding images of your favorite viruses, fungi, bacteria and parasites http://www.instagram.com/asmicrobiology/
Lora Hooper (UT Southwestern) 1: Mammalian gut microbiota: Mammals and their symbiotic gut microbes
https://www.ibiology.org/immunology/gut-microbiota/ Overview: Dr. Hooper studies how the gut microbiota changes during illness or disease and how it influences our ability to fight infections. In part 2, Hooper explains how a healthy gut microbes induce a host protein called RegIIIγ which helps to protect the host from infection by pathogenic gram-positive bacteria. Detailed description: In this lecture, Dr. Hooper introduces us to the fascinating world of human microbiota; the microorganisms that live within our bodies. Although we may think that most bacteria are harmful, Hooper provides ample evidence that symbiotic gut microbes are important to good human health. Her lab is interested in understanding how the microbiota changes during illness or disease and how it influences our ability to fight infections. Using germ-free mice, they were able to demonstrate that a healthy microbiota can shape development of the host immune system and provide protection against dangerous infections like salmonella. In the second part of her talk, Hooper explains how the balance of organisms in the microbiota is maintained. By comparing DNA microarray data from normal mice and germ-free mice, Hooper’s lab was able to look for genes induced by the microbiota. They identified RegIIIγ, an important protein involved in the protection against pathogenic bacteria. They showed that RegIIIγ forms pore complexes in the membranes of gram-positive bacteria and kills them. In mice and humans, the intestinal epithelium is coated with a layer of mucus. Typically, there is a gap between gut bacteria, which are found in the outer part of the mucus layer, and the epithelial cells. Hooper’s lab showed that RegIIIγ helps to maintain this gap by preventing gram-positive bacteria from colonizing the intestinal epithelial surface. This, in turn, prevents infection of the host. Speaker Biography: Although she always was interested in science, Lora Hooper’s love for biology started after taking an introductory class at Rhodes College in Memphis, TN where she was an undergraduate. Hooper continued her graduate education in the Molecular Cell Biology and Biochemistry Program at Washington University in St. Louis where she joined Dr. Jacques Baenziger's lab. For postdoctoral training, she stayed at Washington University, in the lab of Jeffrey Gordon, where she began her studies of the interaction between gut bacteria and host cells and discovered that bacteria have the capacity to modify carbohydrates important for cell signaling. Currently, Hooper is a Professor at The University of Texas Southwestern Medical Center and a Howard Hughes Medical Institute Investigator. She has established one of the handful of mouse facilities that have the capacity to breed germ-free mice. Using these mice, her lab explores the symbiotic relationship between a host and its microbiota with the aim of providing insight into human health. Hooper was a recipient of the Edith and Peter O’Donnell Awards in 2013 and in 2015 she was elected to the National Academy of Sciences.
Views: 6299 iBiology
Sébastien LEMIRE - Technologies for engineering the microbiome
Understanding the role of the gut microbiome in modulating host health and disease will require technologies for localized and long-term monitoring of microbiome and gut functions in vivo. Furthermore, new strategies are needed for precise modulation of microbiomes to enable new diagnostics and therapeutics, since existing approaches for modulating the microbiome can have significant off-target effects. Synthetic biology can provide new tools for studying and manipulating complex microbial communities. We have created strategies for engineering commensal gut bacteria, such as Bacteroides thetaiotaomicron, a major and stable member of the human gut microbiome with synthetic gene circuits and we demonstrated that the y are still functional in mice stably colonized with the engineered bacterium. This work provides a resource for Bacteroides genetic engineering towards future applications as non-invasive diagnostics and therapeutics in the gut microbiome. Furthermore, we have created technologies for the specific knockdown of bacteria living in mixed microbial communities. For example, we engineered CRISPR-Cas antimicrobials that kill bacteria based on their genetic signatures. In addition, we have built a technology platform for engineering phage host range, which enables the creation of well-defined phage cocktails that can kill specific subpopulations of bacteria within mixed microbial consortia. We anticipate that these strategies will be useful for the targeted knockdown of bacteria in complex microbiomes to understand the functional role of these bacteria or achieve therapeutic effects.
B&B: Bacterial attachment and carbohydrate metabolism
Video Highlight from Michaela A. TerAvest on her recently published B&B paper entitled "Regulated expression of polysaccharide utilization and capsular biosynthesis loci in biofilm and planktonic Bacteroides thetaiotaomicron during growth in chemostats." Read the paper on Wiley Online Library: http://onlinelibrary.wiley.com/doi/10.1002/bit.24994/abstract
Views: 606 WileyVideoAbstracts
Medical vocabulary: What does Bacteroides mean
What does Bacteroides mean in English?
Views: 10 botcaster inc. bot
How Scientists Are Hacking Bacteria To Fight Disease
Gut bacteria helps you digest food and keeps your gut healthy but can scientists control this bacteria to fight off disease? Help support DNews by completing this one-question survey http://bit.ly/dnewssurvey Watch More ???? http://dne.ws/1hmhZ0v Read More: Basic computing elements created in bacteria http://www.sciencedaily.com/releases/2015/07/150709132444.htm "Researchers unveil a series of sensors, memory switches, and circuits that can be encoded in the common human gut bacterium. These basic computing elements will allow the bacteria to sense, memorize, and respond to signals in the gut." Designer microbiome: MIT biologists program common gut bacteria http://www.latimes.com/science/sciencenow/la-sci-sn-designer-microbiome-20150709-story.html "Bioengineers are assembling a tool kit for building designer bacteria that doctors could introduce into the microbiome to diagnose, monitor or even treat disease." ____________________ DNews is dedicated to satisfying your curiosity and to bringing you mind-bending stories & perspectives you won't find anywhere else! New videos twice daily. Watch More DNews on TestTube http://testtube.com/dnews Subscribe now! http://www.youtube.com/subscription_center?add_user=dnewschannel DNews on Twitter http://twitter.com/dnews Trace Dominguez on Twitter https://twitter.com/tracedominguez Julia Wilde on Twitter https://twitter.com/julia_sci DNews on Facebook https://facebook.com/DiscoveryNews DNews on Google+ http://gplus.to/dnews Discovery News http://discoverynews.com Download the TestTube App: http://testu.be/1ndmmMq
Views: 50025 Seeker
S. pyogenes glycoside hydrolase family 38 compared with B. thetaiotaomicron glycoside hydrolase family 92
Views: 150 Michael Suits
Realizado por: Ingrid Álvarez, Paola Gamboa y Manuela Gil
Views: 1129 Manuela Gil Corredor
Bacterial Colonization Factors ... Specificity & Stability of Gut Microbiota - Sarkis Mazmanian
July 24-26, 2013 - Human Microbiome Science: Vision for the Future More: http://www.genome.gov/27554404
Find Your Passion – Be a Medical Scientist Like Amy
http://www.labtv.com/Home/Profile?researcherId=1610 Meet Amy Jacobson, a graduate student in the the Fishbach Laboratory at UCSF. Amy's research involves how proteins in the digestive system interact with bacteria in the gut and contributes to trying to reduce inflammation by genetically altering proteins. To learn more about Amy, visit http://www.labtv.com/Home/Profile?researcherId=1610
Views: 16735 LabTV

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